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Unnecessary vitamin B12 shots costing Ontario millions, study finds Most seniors getting B12 shots in province don't need them, researchers say Almost two-thirds of Ontario seniors who received vitamin B12 shots had no evidence of a B12 deficiency, according to a study published in the medical journal JAMA Internal Medicine

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Future studies should also confirm and expand on previous findings showing that a single longitudinal stretch of saphenous vein grafts produces significant increase in the expression and activation of α v integrin, MMP-2, and MMP-9, key molecules in vascular remodeling