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In this sense, a parallel randomized controlled trial also demonstrated that an isocaloric MedDiet in obese and overweight patients led to an increase in SCFA levels, Faecalibacterium strains (linked to butyrate metabolism) and in gene bacterial gene richness, diminishing Ruminococcus gnavus (with potentially proinflammatory properties) and decreasing systemic inflammation [285]
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It showed a decreasing trend in the right basal ganglia, glutamine–glutamate decreased in the right basal ganglia, and a decreasing trend in the left basal ganglia, and glutamate and GABA showed no changes
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