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The high prevalence of hypertension and diabetes in Afro-Caribbeans in the West could be directly related to the incidence of G6PD deficiency in those populations [6]
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This mechanism establishes OLA as a promising anti-fibrotic therapeutic candidate ( Mitochondria-targeted antioxidants or CYP2E1 inhibition prevents this toxicity, highlighting CcO dysfunction as a key pathological mechanism ( Daphnia magna through its reactive metabolite NAPQI