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Following GPx-mediated H 2 O 2 consumption, residual hydrogen peroxide undergoes Fenton-type redox reactions with Fe 2+ ions, generating Fe³ + species that coordinate with Tiron through catechol moieties to form a stable ferri-Tiron complex [Fe(C 6 H 4 Na 2 O 8 S 2 )]³ +

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