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These findings collectively highlight that PTSD is associated with reproducible patterns of gut dysbiosis, characterized by reduced SCFA-producing taxa and increased inflammatory pathobionts, supporting a functional link between microbial imbalance and psychiatric vulnerability

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1999, plasma half-life approximately two hours intravenous in healthy male volunteers) measured growth hormone release as the sole pharmacodynamic readout and did not measure plasma cortisol, ACTH, or prolactin [4]