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Arrestin 3, dynamin and GRK2 also participate to MOR resensitization on the activation of potassium channels in neurons from the locus coeruleus of mice treated during 6 days with morphine (Dang et al., 5 ]-enkephalin exposure (Quillinan et al., 2011)

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53.4A) (see above) results in depletion of NADPH, which is the cofactor essential for maintaining glutathione in the reduced state