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Previously, it has been shown that vitamin E pre-treatment of neutrophils isolated from GSR-deficient human subjects rescued their pentose phosphatase shunt activity (33), a metabolic reaction responsible for the generation of NADPH, a substrate for neutrophil respiratory burst
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Research shows that MTHFR gene mutations can affect folate metabolism and methylation, two processes vital for DNA repair, hormone balance, detoxification, mental health, and fertility