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(One important accuracy note: NAD+ is a coenzyme rather than a peptide, but it's central enough to longevity research to belong in any serious overview of the category.) The Four Pathways of Longevity Research The compounds below map to four distinct aging-research pathways: NAD+ metabolism → NAD+ Telomere and pineal-gland biology → Epithalon Mitochondrial-derived signaling → MOTS-c Gene expression and collagen / skin aging → GHK-Cu 1