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Mechanical agitation, rapid hydration, and direct injection onto the lyophilised cake all cause shear stress that denatures the peptide's tertiary structure

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[DOI] [PubMed] [Google Scholar] 130.Jenkins T., Aston K., Carrell D., DeVilbiss E., Sjaarda L., Perkins N., Mills J.L., Chen Z., Sparks A., Clemons T